DESCRIPTION

Cellufine GH-25 provides a rapid means of salt removal and buffer exchange for protein solutions. The semi-rigid spherical cellulose beads allow high flow rates with little compression of the column bed. The separation mechanism is based on differential solute access into the chromatographic bead.

Whereas large molecules (above 3 kD) are excluded from the packing and pass quickly through the column, small molecules (salts) diffuse into the bead and are thus retained longer. GH-25 can be used to remove alcohols, salts, detergents, fluorochromes, sugar, etc., from virtually any protein solution. It is compatible with most solvents and is stable from pH 1 - 14.