Anti-Smad2 Monoclonal Antibody
产品名称: Anti-Smad2 Monoclonal Antibody
英文名称: Anti-Smad2 Monoclonal Antibody
产品编号: K000096M
产品价格: 0
产品产地: 北京
品牌商标: Solarbio
更新时间: 2024-12-25T14:11:45
使用范围: null
北京索莱宝科技有限公司
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Anti-Smad2 Monoclonal Antibody
品牌:Solarbio | 货号:K000096M
商品货号: 商品品牌: 规格 基本售价: 选择规格 K000096M-50ul Solarbio 50ul 960.00元 K000096M-100ul Solarbio 100ul 1600.00元
英文名称 Mouse Smad2 Monoclonal Antibody 应用2 WB ICC 克隆类型2 Monoclonal Antibody 别名 Smad2 应用 WB,ICC 稀释比例 WB1:500 ICC1:100 交叉反应 Human 蛋白分子量 60kDa Gene ID 4087 保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. 亚型 IgG1 免疫原 Purified recombinant human Smad2 protein fragments expressed in E.coli. 性状 Lyophilized or Liquid Swiss Prot Q15796 克隆号 6H5-E3-C11 克隆类型 Monoclonal Antibody 来源 Mouse 背景资料 The protein encoded by this gene belongs to the SMAD,a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C.elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.This protein mediates the signal of the transforming growth factor (TGF)-beta,and thus regulates multiple cellular processes,such as cell proliferation,apoptosis,and differentiation.This protein is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein.In response to TGF-beta signal,this protein is phosphorylated by the TGF-beta receptors.The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4.The association with SMAD4 is important for the translocation of this protein into the nucleus,where it binds to target promoters and forms a transcription repressor complex with other cofactors.This protein can also be phosphorylated by activin type 1 receptor kinase,and mediates the signal from the activin.Alternatively spliced transcript variants have been observed for this gene.[provided by RefSeq,May 2012]