Recombinant Human Hepatocyte Growth Factor (Human HGF)
产品名称： Recombinant Human Hepatocyte Growth Factor (Human HGF)
英文名称： Recombinant Human Hepatocyte Growth Factor (Human HGF)
产品编号： 92055ES10
产品价格： 815.00
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2024-03-21T15:37:50
使用范围： null
| 规格 | 价格 |
| 10μg | 815.0 |
| 50μg | 3285.0 |
| 100μg | 4925.0 |
| 500μg | 12805.0 |
| 1mg | 19715.0 |
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Product Information
Product Description
HGF is a potent, mesenchymally-derived mitogen for mature parenchymal hepatocytes, and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include the induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. HGF, also known as scatter factor and hepatopoietin A, is a pleiotropic protein in the plasminogen subfamily of S1 peptidases. It is a multidomain molecule that includes an N-terminal PAN/APPLE‑like domain, four Kringle domains, and a serine proteinase-like domain that has no detectable protease activity.
Product Properties
|
Synonyms |
Scatter Factor (SF), Hepatopoietin (HPTA) |
|
Accession |
P14210 |
|
Gene ID |
3082 |
|
Source |
CHO-derived Human HGF protein, Gln32-Ser728 |
|
Molecular Weight |
88~90 kDa (single chain), 59~61 kDa (alpha chain), 30~34 kDa (beta chain), on SDS-PAGE under reducing conditions. |
|
Tag |
None |
|
Purity |
> 95% by SDS-PAGE. |
|
Biological Activity |
ED50 < 10.0 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1.0 × 105 units/mg. |
|
Endotoxin |
< 0.2 EU per 1μg of the protein by the LAL method. |
|
Formulation |
Lyophilized after extensive dialysis against PBS. |
|
Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O or PBS up to 100 μg/ml. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. |
Shipping and Storage
The products are shipped with ice pack and can be stored at -80℃ for 1 year.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
- Avoid repeated freeze-thaw cycles.
- For your safety and health, please wear lab coats and disposable gloves for operation.
- For research use only.
HB240227