CAPN9 Rabbit pAb (APR23518N)
产品名称: CAPN9 Rabbit pAb (APR23518N)
英文名称: CAPN9 Rabbit pAb (APR23518N)
产品编号: APR23518N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
分子量:Calculated MW: 76kDa/79kDa Observed MW: Refer to figures 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 总结:Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.