DSS诱导的肠炎模型
产品名称: DSS诱导的肠炎模型
英文名称: DSS induced IBD model
产品编号: BDA-IF005
产品价格: 询价
产品产地: null
品牌商标: null
更新时间: null
使用范围: null
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- 邮编 : 201203
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DSS诱导的肠炎模型
实验方案:
1) 将老鼠随机分组;
2) 对照组:每天饮用灭菌水;
3) 模型组每天饮用3.5%DSS至第6天,从第7天开始换为灭菌水,至第12天;
4) 实验开始后,每天对老鼠进行观察,称重和评分;
5) 肠炎观察指标包括: 体重; 拉稀程度;结肠病变情况等
Brief protocol of DSS induced IBD model:
1) Mice: 6-8 weeks old, female; Random divided into several groups;
2) DSS concentration: 3.5%, control group treated with drink water;
3) DSS treatment: DSS in drink water from Day 1 to Day 6 and changed to drink water from Day 7 to Day 12;
4) Observation: Mice are observed by measuring body weight twice a week in the first cycle. When obvious weight loss appears, mouse weight is measured on daily basis.
5) Clinical colitis analysis: colitis scoring based on: Weight loss, Rectal bleeding, Colon shortening, Colon tissue damage.