Dansylcadaverine
产品名称： Dansylcadaverine
英文名称： Dansylcadaverine
产品编号： 30432
产品价格： 0
产品产地： sigma
品牌商标： sigma
更新时间： null
使用范围： null
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- 邮编 : 200030
- 所在区域 : 上海
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产品名称
Frequently Asked Questions
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Application
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Dansylcadaverine (MDC), an autofluorescent dye, is used to monitor autophagy. MDC accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.
Biochem/physiol Actions
Inhibitor of the fibrin-stabilizing fator;1 Inhibitor of epidermal growth factor (EGF) internalization;2 Fluorescent substrate for the assay of transamidating enzymes.3,4
The autofluorescent dye dansylcadaverine, or monodansylcadaverine (MDC), is commonly used to monitor autophagy. MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.
Other Notes
Solubility of dansylcadaverine is tested in methanol (10 mg/mL). It has also been reported that dansylcadaverine is soluble in DMSO and acetic acid.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
air sensitive, handled under inert gas
性质
| Related Categories | Alphabetical, Autophagy, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, |
| product line | BioReagent |
| assay | ≥99.0% (HPLC) |
| mp | 137-140 °C |
| fluorescence | λex 335 nm; λem 518 nm in methanol |
| λex 338 nm; λem 500 nm (Reaction product) | |
| suitability | suitable for fluorescence |
| solubility | Do you have solubility information on this product that you would like to share? |
| storage temp. | −20°C |