TET1 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TET1 抗体

TET1 抗体

商家询价

产品名称: TET1 抗体

英文名称: TET1 Antibody

产品编号: XY55307-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 TET1 抗体Applications

In-house applications ELISA     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
 
Recommended dilution  
 TET1 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information TET1 抗体
Immunogen Peptide Full name Tet oncogene 1
Calculated molecular
weight
235 kDa Observed molecular 
weight
 
GenBank accession 
number
NM_030625 Gene ID (NCBI) 80312
Gene symbol TET1 Synonyms BA119F7.1, CXXC6, FLJ10839, FLJ41442, KIAA1676, LCX, tet oncogene 1, TET1
Background

TET1 ( also named CXXC6, KIAA1676 or LCX), belongs to the TET family (Tet1-3) which catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). TET1 binds throughout the genome of embryonic stem cells, with the majority of binding sites located at transcription start sites of CpG-rich promoters and within genes. Knockdown of Tet1 in preimplantation embryos resulted in a bias towards trophectoderm differentiation.Tet1 can associate with either active or repressed transcriptional states and be identified as new epigenetic factor implicated in the establishment and/or maintenance of a pluripotent epigenetic state during early embryonic development.Tet1 is highly expressed in ES cells and is rapidly downregulated upon differentiation. This antibody is specific to TET1. TET1 抗体

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