别名：IDDM20; LNK

产品概述：Carrier-free (BSA/glycerol-free) SH2B3 mouse monoclonal antibody, clone LBI2D8

总结：This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. [provided by RefSeq, May 2010]