FITC标记的类肿瘤性抗原MA3抗体
产品名称： FITC标记的类肿瘤性抗原MA3抗体
英文名称： Anti-PNMA3/FITC
产品编号： HZ-12743R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PNMA3/FITC Conjugated antibody
FITC标记的类肿瘤性抗原MA3抗体
| 英文名称 | Anti-PNMA3/FITC |
| 中文名称 | FITC标记的类肿瘤性抗原MA3抗体 |
| 别 名 | MA3; MA5; MGC132756; MGC132758; Paraneoplastic antigen Ma3; Paraneoplastic cancer testis brain antigen; Paraneoplastic Ma antigen 3; PNMA 3; PNMA3; PNMA3_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Horse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PNMA3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Subcellular Location: Nucleus > nucleolus. Tissue Specificity: Expressed at high levels in the brain and testis. Expressed at lower levels in the heart, trachea and kidney. Similarity: Belongs to the PNMA family. Contains 1 CCHC-type zinc finger. Database links: Entrez Gene: 29944 Human GenBank: NP_037496 Human Omim: 300675 Human SwissProt: Q9UL41 Human Unigene: 449627 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
该基因编码的蛋白属于副肿瘤抗原MA（PNMA）家族，与逆转录病毒Gag蛋白具有同源性。PNMA抗原在大脑中高度表达，并且在一系列与严重神经表型相关的肿瘤中高度表达。PMID:16407312报道了在该基因中存在一个功能性-1核糖体移码信号（包括七核苷酸移位基序，后跟3′假结结构），然而，该移码产物尚未被鉴定。此外，还发现了编码不同异构体的剪接转录体变异体。