PER1 Rabbit pAb (APR28236N)
产品名称: PER1 Rabbit pAb (APR28236N)
英文名称: PER1 Rabbit pAb (APR28236N)
产品编号: APR28236N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB (Primary mouse liver, Drosophila melanogaster, Mus musculus)
分子量:Calculated MW: 91kDa/136kDa Observed MW: 50KDa 细胞定位:Cytoplasm, Nucleus 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200 总结:This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described.