重组小鼠脂肪细胞补体相关蛋白30(Acrp30)
产品名称: 重组小鼠脂肪细胞补体相关蛋白30(Acrp30)
英文名称: Recombinant Mouse Adipocyte complement-related 30 kDa protein
产品编号: HZ1183
产品价格: 0
产品产地: 中国/上海
品牌商标: 沪震生物
更新时间: 2023-08-17T10:24:20
使用范围: null
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重组小鼠脂肪细胞补体相关蛋白30(Acrp30)
中文名称:重组小鼠脂肪细胞补体相关蛋白30(Acrp30)
英文名称:Recombinant Mouse Adipocyte complement-related 30 kDa protein
产品规格:10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Glu18-Asn247在N端含有His标签。
Acrp30质量控制:>95%(还原性SDS-PAGE)
Acrp30制剂:冻干品
Acrp30保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Acrp30复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Acrp30:
Adiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
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