FITC标记的转录因子SOX30抗体
产品名称： FITC标记的转录因子SOX30抗体
英文名称： Anti-SOX30/FITC
产品编号： HZ-13611R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SOX30/FITC Conjugated antibody
FITC标记的转录因子SOX30抗体
| 英文名称 | Anti-SOX30/FITC |
| 中文名称 | FITC标记的转录因子SOX30抗体 |
| 别 名 | Sex determining region Y box 30; Sox30 protein type II; SRY box 30; SRY related HMG box 30; Transcription factor SOX 30; SOX30_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 干细胞 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 82kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SOX30 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Sox-30 encodes a member of the Sox (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox-30 is expressed in testis and may act as a transcriptional regulator after forming a protein complex with other proteins. Sox-30 may be involved in the differentiation of developing male germ cells. Two transcript variants encoding distinct isoforms have been identified for the human Sox-30 gene. Sox family transcription factors influence cell differentiation, development and sex determination. Sox-30 contains a unique DNA binding domain, known as the high mobility group (HMG) box, that is related to that of the testis determining gene, SRY. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. Several Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Function: SOX30 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein may be involved in the differentiation of developing male germ cells. Subcellular Location: Nuclear Tissue Specificity: Expressed in testis. Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 11063 Human Entrez Gene: 214105 Mouse Omim: 606698 Human SwissProt: O94993 Human SwissProt: Q8CGW4 Mouse Unigene: 744348 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Sox-30编码Sox(SRY相关的HMG-box)家族中与胚胎发育调节和细胞命运测定有关的转录因子成员。SOX-30在睾丸中表达，并在与其他蛋白形成蛋白复合物后起转录调节作用。SOX-30可能参与发育男性生殖细胞的分化。两种编码不同亚型的转录变体已被鉴定为人类SOX-30基因。SOX家族转录因子影响细胞分化、发育和性别决定。Sox-30包含一个独特的DNA结合结构域，称为高迁移率基团（HMG）盒，它与睾丸决定基因SRY有关。SOX基因的高度复杂的群集至少在40个不同的位点聚集，在不同的动物谱系中迅速分化。一些Sox基因已经被鉴定出来，而且这个家族的成员在进化过程中被证明是保守的，并且在动物发育过程中起着关键作用。