PFKFB1 (Human) Recombinant Protein (Q01)
产品名称： PFKFB1 (Human) Recombinant Protein (Q01)
英文名称： PFKFB1 (Human) Recombinant Protein (Q01)
产品编号： H00005207-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human PFKFB1 partial ORF ( NP_002616, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNME
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 5207
- GeneBank Accession#:
- NM_002625
- Protein Accession#:
- NP_002616
- Gene Name:
- PFKFB1
- Gene Alias:
- F6PK,HL2K,MGC116715,MGC116717,PFRX
- Gene Description:
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
- Omim ID:
- 311790
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq
- Other Designations:
- 6PF-2-K/Fru-2,6-P2ASE liver isozyme,OTTHUMP00000023391,fructose-2,6-bisphosphatase,fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
- Gene Pathway
- Related Disease