分子量：Calculated MW: 38kDa/45kDa

细胞定位：Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein

稀释方法：IF 1:50 - 1:200

总结：This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.