Anti-ISLR2/FITC Conjugated抗体-抗体-抗体-生物在线
上海沪震实业有限公司
Anti-ISLR2/FITC Conjugated抗体

Anti-ISLR2/FITC Conjugated抗体

商家询价

产品名称： Anti-ISLR2/FITC Conjugated抗体

英文名称： Anti-ISLR2/FITC

产品编号： YB--9025R-FITC

产品价格： null

产品产地： 中国/美国

品牌商标： Ybscience

更新时间： 2023-08-17T10:24:20

使用范围： 科研使用

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 Anti-ISLR2/FITC Conjugated抗体

产品编号 YB-9025R-FITC
英文名称 Anti-ISLR2/FITC
中文名称 FITC标记的ISLR2蛋白抗体
别    名 Immunoglobulin superfamily containing leucine-rich repeat protein 2; Leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein; ISLR2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 77kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ISLR2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. ISLR2 (immunoglobulin superfamily containing leucine-rich repeat 2), also known as LINX (leucine-rich repeat domain and immunoglobulin domain-containing axon extension protein), is a 745 amino acid single-pass membrane protein that contains five LRR repeats, one Ig-like (immunoglobulin-like) domain, a LRRCT domain and one LRRNT domain. ISLR2 exists as a homomultimer and is essential for axon extension during neural development. The gene encoding ISLR2 maps to human chromosome 15q24.1.

Function:
Required for axon extension during neural development (By similarity). 

Subunit:
Homomultimer. Interacts with NTRK1/TrkA (By similarity).

Subcellular Location:
Cell membrane; Single-pass membrane protein (By similarity).

Similarity:
Contains 1 Ig-like (immunoglobulin-like) domain.
Contains 5 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 57611 Human

Entrez Gene: 320563 Mouse

SwissProt: Q6UXK2 Human

SwissProt: Q5RKR3 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applicationS