重组人UBE2K(带His标签)
产品名称: 重组人UBE2K(带His标签)
英文名称: Recombinant Human Ubiquitin-conjugating Enzyme E2 K, His
产品编号: HZ4636
产品价格: 0
产品产地: 中国/上海
品牌商标: 沪震生物
更新时间: 2023-08-17T10:24:20
使用范围: null
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重组人UBE2K(带His标签)
中文名称:重组人UBE2K(带His标签)
英文名称:Recombinant Human Ubiquitin-conjugating Enzyme E2 K, His
产品规格:10μg
分子量:Approximately 23.4kDa,a single non-glycosylated polypeptide chain containing 200 amino acids(a.a.)of human UBE2K and 8 a.a.vector sequence including 6×His tag at N-terminus.
储存条件:冷冻(-20℃)
概述
Ubiquitin-conjugating enzyme E2 K belongs to the ubiquitin-conjugating enzyme family and is encoded by the UBE2K gene in humans.The ubiquitin-conjugating enzymes,also known as E2 enzymes and more rarely as ubiquitin-carrier enzymes,take part in the second step in the ubiquitination reaction.In this reaction,E1 activates the ubiquitin by covalently attaching the molecule to its active site cysteine residue.The activated ubiquitin is then transferred to an E2 cysteine and then the E2 molecule binds E3 via a structurally conserved binding region.The ubiquitination reaction can modify proteins and regulate protein degradation.The UBE2K has been shown to interact with Huntingtin and RNF2.Additionally,it has been implicated in the degradation of huntingtin and suppression of apoptosis.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
特别提示:本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!