ARHGEF3 (Human) Recombinant Protein (Q01)
产品名称： ARHGEF3 (Human) Recombinant Protein (Q01)
英文名称： ARHGEF3 (Human) Recombinant Protein (Q01)
产品编号： H00050650-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ARHGEF3 partial ORF ( NP_062455, 33 a.a. - 142 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- EPSNKRVKPLSRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLK
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 50650
- GeneBank Accession#:
- NM_019555
- Protein Accession#:
- NP_062455
- Gene Name:
- ARHGEF3
- Gene Alias:
- DKFZp434F2429,FLJ98126,GEF3,MGC118905,STA3,XPLN
- Gene Description:
- Rho guanine nucleotide exchange factor (GEF) 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- 59.8 kDA protein,Rho guanine nucleotide exchange factor 3,RhoGEF protein,exchange factor found in platelets and leukemic and neuronal tissues, XPLN