中文名称 转录因子SOX-11蛋白重组兔单克隆抗体 
别    名 SRY (sex determining region Y) box 11; SRY related HMG box gene 11; Transcription factor SOX-11; SOX11_HUMAN.   
研究领域 肿瘤  细胞生物  神经生物学  信号转导  干细胞  转录调节因子  表观遗传学   
抗体来源 Rabbit 
克隆类型 Monoclonal 
克 隆 号 1E8 
交叉反应 (predicted: Human, ) 
产品应用 WB=1:500-1000 IP=1:20-100 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. 
分 子 量 47kDa 
细胞定位 细胞核  
性    状 Liquid 
浓    度 1mg/ml 
免 疫 原 Recombinant human SOX11 protein (1-100aa):  
亚    型 IgG 
纯化方法 affinity purified by Protein A 
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 
保存条件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 
PubMed PubMed 
产品介绍 This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
 
Function:
Transcriptional activator.
 
Subcellular Location:
Nucleus.
 
Tissue Specificity:
Mainly expressed in the developing central nervous system.
 
Similarity:
Contains 1 HMG box DNA-binding domain.
 
SWISS:
P35716
 
Gene ID:
6664
 
Database links:
Entrez Gene: 6664 HumanEntrez Gene: 20666 MouseEntrez Gene: 84046 RatOmim: 600898 HumanSwissProt: P35716 HumanSwissProt: Q7M6Y2 MouseSwissProt: P0C1G9 RatUnigene: 432638 HumanUnigene: 41702 MouseUnigene: 466344 MouseUnigene: 162854 Rat
 
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.