PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb (APR26767N)
产品名称: PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb (APR26767N)
英文名称: PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb (APR26767N)
产品编号: APR26767N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围:
安诺伦(北京)生物科技有限公司
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分子量:Calculated MW: 52kDa/61kDa/66kDa/73kDa Observed MW: 65kDa 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 总结:This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.